Brain Tumour Funders' Collaborative Research Grants
Brain Tumour Foundation of Canada has formed a partnership with seven other non-profit philanthropic and advocacy organizations from the United States, to launch the Brain Tumor Funders' Collaborative. These organizations are:
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American Brain Tumor Association (ABTA)
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Brain Tumour Foundation of Canada
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Brain Tumor Society (BTS)
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Children’s Brain Tumor Foundation (CBTF)
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Goldhirsh Foundation
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James S. McDonnell Foundation
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National Brain Tumor Foundation (NBTF)
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Sontag Foundation
On January 20, 2010, the Brain Tumor Funders’ Collaborative (BTFC) announced the award of 11 one-year feasibility grants of $100,000 each to teams of researchers and clinicians developing the types of tools needed to translate scientific discoveries into effective new treatments for brain cancer patients. The BTFC’s second joint initiative for brain tumor research is intended to accelerate the testing of different kinds of brain tumor response markers – reliable, easily monitored biological signals that can reveal if and how a tumor is responding to therapies.
"Although the current armamentarium for treating brain tumors is limited, a number of new treatment options will be coming online," said Suan Marshall of the Brain Tumour Foundation of Canada. "Validated tumor response markers will be a necessary component of research and clinical decision making."
Read the Press Release Here (pdf document).
The eleven funded projects are:
Children’s Hospital Boston
Investigator: Edward R. Smith
Urinary Biomarkers for Non-invasive Assessment of Therapeutic Efficacy in Glioma
Emory University School of Medicine
Investigator: Erwin G. Van Meir
Development of Protein Arrays for the Detection of Biomarkers in the CSF of Brain Tumor Patients
Johns Hopkins University
Investigator: Jaishri O. Blakeley
Amide Proton Transfer MR Imaging to Assess Tumor Response in Patients with Gliomas
Johns Hopkins University
Investigator: Luis A. Diaz
Circulating Tumor DNA as a Dynamic Biomarker in Malignant Gliomas
Johns Hopkins University
Investigator: Alena Hoska
Non-invasive Assessment of Glutamate in Glioblastoma Multiforme: Effect of Treatment
Massachusetts General Hospital
Investigator: Bob S. Carter
Exosome Analysis: A Non-Invasive Approach to Monitor Treatment Responses in Glioma Patients
Memorial Sloan-Kettering Cancer Center
Investigator: Andrew B. Lassman
Molecular Determinants of [18F]FACBC-PET Imaging in Brain Tumors
University of California (David Geffen School of Medicine at UCLA)
Investigator: Whitney B. Pope
Combining Genomics with Physiologic Imaging Biomarkers to Predict and Follow Treatment Response in Glioma
University of Texas MD Anderson Cancer Center
Investigator: Kenneth D. Aldape
A combined molecular and clinical predictor of progression vs. pseudoprogression in newly diagnosed GBM.
University of Washington
Investigator: Kristin R. Swanson
Patient-specific Metrics of Treatment Response
Vanderbilt University Medical Center
Investigator: Kyle D. Weaver
Monitoring Response to Therapy in Malignant Glioma Patients Using Blood-Based Epigenomic and Proteomic Biomarkers
More information about the BTFC and its funding initiative is available at www.braintumorfunders.org.
Brain tumor facts are available at http://www.nci.nih.gov/cancertopics/types/brain/
On March 14, 2006, with a goal to promote collaborative, innovative and novel research approaches for pre-clinical systems to accelerate more effective outcomes for patients with gliomas, this joint funding initiative chose three, $2 million, multi-year grants:
Project Title: Tumor Stem Cell-Based Drug Discovery for Adult and Pediatric Glioma
Sponsoring Institution: Kennedy- Krieger Institute, Johns Hopkins University, Baltimore, Maryland
Project Manager: Dr. John Laterra
Project Title: Molecularly Guided Clinical Trials for Glioma
Sponsoring Institution: David Geffen School of Medicine at UCLA
Program Manager: Dr. Paul Mischel
Project title: Identifying and Overcoming Resistance Mechanisms in Glioblastomas: A Joint EORTC-RTOG Effort
Sponsoring Institution: American College of Radiology/Radiation Therapy Oncology Group
Project Manager: Dr. Minesh Mehta
Read the press release here
Thank you to all applicants! Please find full descriptions at
North American Brain Tumour Funders' Collaborative
Also, new in 2006, we are a member of the North American Brain Tumour Funders' Collaborative, a group of eight organizations dedicated to funding three $2 million dollar grants to accelerate brain tumour research.
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À 2003 Brain Tumour Foundation of Canada 1.800.265.5106
Charitable Registration #BN118816339RR0001 |